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My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

The fragile p-value

5 October 2020 | | EYE - General
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

The world in union

4 October 2023 |
"It’s the world in union, the world as one…” Hearing these lyrics as a sports fan means only one thing: it’s time for the Rugby World Cup! This four-yearly sporting extravaganza should hit your TV screens around the same time...

Can OCT predict Alzheimer’s disease?

5 February 2020 | | EYE - Imaging, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

Exploiting nature’s randomised trials of eye disease

1 December 2022 | | EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - Orbit
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

A window to 2024 and beyond?

3 April 2024 | | EYE - Cornea
The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

Semaglutide and vision loss: A new concern for NAION risk?

4 December 2025 | | EYE - Neuro-ophthalmology
This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as transformative agents in...

The Spectacle Makers’ Charity takes up the challenge of glaucoma in Nigeria

16 August 2022
The Glaucoma-NET was established by the VISION 2020 LINKS Programme in 2021 to address the high levels of irreversible blindness due to glaucoma in low-income countries. It aims to preserve the sight of people with glaucoma through bringing together patients, clinicians, researchers, NGOs and Ministries of Health, with a lasting and sustainable impact.

Conference Report: ARVO 2025 Annual Meeting

5 June 2025 | | Newsround, News, Report, Conferences, Events, US
The Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting was held at the Salt Palace Convention Centre in Salt Lake City, US. This prestigious event brought together experts in vision and ophthalmology from around the world for...

Orbis and Heidelberg Engineering announce expansion of collaboration during a special visit to the Flying Eye Hospital in Rwanda

23 September 2025 | charity, collaboration, education, Africa, international
The medtech imaging and data solutions company, Heidelberg Engineering, and sightsaving nonprofit, Orbis, have come together on board the Orbis Flying Eye Hospital during its latest programme in Kigali, Rwanda, to announce the expansion of their collaboration in making educational...

UKPGS (UK Paediatric Glaucoma Society) Meeting 2023

27 January 2023
by SP Gurney The UK Paediatric Glaucoma Society (UKPGS) 2023 annual meeting took place on 27 January at the Cavendish Conference Centre in London. Professor Sir Peng Khaw, UKPGS President, welcomed nearly 100 delegates from around the world, with representation...