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Decontamination and sterilisation of surgical instruments and medical devices

Ann-Marie Ablett is a Theatre Nurse and Team Leader who volunteers with Orbis. This has allowed her to gain a wealth of experience on ophthalmic procedures, nursing in under-privileged parts of the world, leadership, management and use of scarce resources....

Polymerase chain reaction evaluation of infectious multifocal serpiginoid choroiditis

This paper presents a retrospective review of infectious agents associated with multifocal serpiginous choroiditis (MSC) based on polymerase chain reaction (PCR) evaluation and specific antimicrobial therapy. The study included 13 patients with MSC who were evaluated with PCR for the...

Incidence, microbiological profile and in vitro antimicrobial susceptibility of IK

This is a retrospective single centre study of all patients (with corneal scraping) including their demographic factors, microbiological profiles, and in vitro antibiotic susceptibility of infectious keratitis (IK), studied between 2007 and 2019. The incidence of IK was 34.7/100,000 people...

Medical and eye health teams defy odds to deliver treatments for trachoma in Ethiopia, but millions worldwide risk return of disease amid UK aid cuts

Ophthalmologists, nurses, and eye health workers in Ethiopia defied the odds to treat millions with trachoma-fighting antibiotics and surgeries - despite cuts to UK Aid assistance threatening eye care. This World Neglected Tropical Diseases Day Orbis, the international eye care...

How to diagnose and treat Acanthamoeba keratitis

Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery

See also Simulated ocular surgery and Simulated ocular surgery - strabismus surgery In this second article on ocular surgery simulation, we will discuss how vitreoretinal surgery can be simulated using high tech virtual reality modalities such as the Eyesi, as...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Augmented surgery for monocular elevation deficiency

The outcomes are described for augmented lateral rectus superior transposition in cases of acquired monocular elevation deficiency (MED) associated with large hypotropia in primary gaze. The lateral rectus was transposed superiorly and reinserted on sclera between the temporal margin of...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Managing cataract surgery in a patient with diabetic maculopathy

A 56-year-old type 2 diabetic with previously treated bilateral diabetic maculopathy develops a cataract requiring surgery in the right eye. He has had grid laser previously, followed intermittently by intravitreal triamcinalone, Avastin and more recently Lucentis in both eyes. His...

The disease burden of AMD

In this multi-centre, prospective, observational, time and motion study the authors assessed the time burden of managing wet AMD for doctors, staff, patients and caregivers in the USA. The study spanned the period from March 2011 to August 2012, and...