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MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...Jury duty
Until a few years ago doctors were exempt from jury duty. I am glad that this exemption was lifted as the stint I did at the crown court in Swansea recently was one of the most illuminating two weeks I...Lost in translation
The article that follows is a collection of reflections and observations by Peter (British) and Nathan (Singaporean) living and working in each other’s countries. Peter Cackett “Best thing about this place is it’s not still full of pompous ex-colonials who...Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting
The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...An anterior segment lump: a diagnostic and treatment challenge
Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...What's trending Aug/Sep 2018
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #QueenElizabeth #cataract It is well and truly summer! Queen Elizabeth was spotted in her sunnies during recent events, not just...What's trending Jun/Jul 2022
A round-up of the eye-related hot topics that have been trending over the last few weeks. #Polishdoctor #UkraineConflict #familysight Polish doctor Professor Rejdak’s team saved a Ukrainian family’s eyesight after a bomb hit their home. Olena Selichzianowa and her 5-year-old...Effective treatment for rare sight-threatening infection
A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.Portable corneal topography – exploration of a prototype
Ophthalmic imaging devices, such as corneal topographers, are not widespread in the developing world. A small device that connects to a smartphone might be a solution to improve developing nation access to corneal imaging. I recently had the opportunity to...
