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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

The use of toxin in paediatric strabismus

4 December 2025 | | EYE - Paediatrics
Strabismus is a common condition that affects up to 5% children and can be associated with abnormal visual development, double vision, loss of depth perception and impaired binocularity [1]. It can also cause cosmetic concerns, negatively impact psychosocial wellbeing and...

Apr/May 2014 Quiz 1

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 45-year-old man presents with left-sided epiphora. During a dacrocystorhinostomy (DCR), the wall of the lacrimal sac was noted to be bulky. The sac wall is biopsied and sent for routine histopathology examination. The pathologist notes a distinctive feature...

Women-led, solar powered eye centres to treat 1 million people at risk of avoidable blindness in India

22 April 2022
One million people at risk of avoidable blindness in West Bengal, India, now have access to eye care thanks to the opening of nine environmentally friendly Green Vision Centres, five of which are led by women.

Strabismus in thyroid eye disease

1 April 2017 | | EYE - Paediatrics, EYE - Strabismus
Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...

Ocular electrophysiology

1 April 2014 | | EYE - Oculoplastic, EYE - Orbit
A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...

How to diagnose and treat Acanthamoeba keratitis

1 February 2019 | | EYE - Cornea, EYE - General
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

3 October 2022 | | EYE - General
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

Headset perimetry

3 April 2023 | | EYE - General
Visual field analysers are traditionally large table mounted devices, designed specifically for field capture and analysis. Over the last year or so a number of companies have started to disrupt this space with the introduction of headset-based field analysers, mostly...

Hype or helpful: ChatGPT

5 June 2023 | | EYE - General
It would have been hard to miss all the attention chatbots have received over the last few months. Whilst ChatGPT is easily the most well-known example of the large language models that have become so widespread of late, artificial intelligence...

Measuring patient-reported outcomes after refractive surgery to assess patient satisfaction

1 June 2019 | | EYE - Cataract, EYE - Refractive, EYE - General
Patient-reported outcomes enable surgeons to evaluate patients’ symptoms and satisfaction after laser vision correction. The great majority of patients are pleased with their outcomes from laser vision correction, whether it is with photorefractive keratectomy, laser in-situ keratomileusis (LASIK), or small...

Evolving towards an interventional glaucoma mindset

2 February 2024 | | EYE - Glaucoma
Traditionally, a newly diagnosed glaucoma patient would be treated first with medical therapy. As the disease progressed or the initial intervention failed to adequately control intraocular pressure (IOP), clinicians would add more drops, selective laser trabeculoplasty (SLT), repeated SLT and...