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Ocular Immunology and Inflammation journal cover image

Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis

1 December 2022 | | EYE - Vitreo-Retinal | Behçet’s disease, interleukin-6, juvenile idiopathic arthritis, rheumatoid arthritis, systemic lupus erythematosus, uveitis
This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

1 August 2024 | | EYE - Neuro-ophthalmology
Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

Changes in retinal and choroidal microcirculation after strabismus surgery

4 August 2025 | | EYE - Strabismus
The aim was to evaluate retinal and choroidal microcirculation using optical coherence tomography angiography after strabismus surgery. This was a cross-sectional observation study of 44 eyes of 44 patients. Patients were split into three groups: (1) one-muscle horizontal surgery (n=9);...
Ophthalmology journal front cover image.

Use of immunomodulatory treatment for non-infectious uveitis: an International

18 December 2025 | | EYE - Vitreo-Retinal
Two-hundred-and-twenty-one group members from 53 countries completed a questionnaire on their indications, investigations and use of conventional and biologics and follow-up of treated patients. Main indications to start systemic immunomodulatory drugs were: uveitis not controlled by oral prednisolone (94.1%), specific...

Childhood glaucoma

2 October 2025 | | EYE - Paediatrics, EYE - Glaucoma
When a child is given a diagnosis of glaucoma, the impact upon that child and their family is enormous; equivalent to the diagnosis of a cancer [14]. This previously published article (2019) outlines the knowledge, techniques and approaches that offer...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Unconscious bias

1 April 2019 | | EYE - General
Swansea University invited me to an Away Day. There was a whole day of lectures planned at a hotel conference suite just outside Swansea but due to clinic commitments I only caught the afternoon session; a ‘workshop’, on how to...

Aug/Sep 2017 Quiz

1 August 2017 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....

Jun/Jul 2017 Quiz

1 June 2017 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 57-year-old female patient presented with gradual painless diplopia over the last six months. Examination revealed restricted upward eye movements and 4mm proptosis which did not increase with Valsalva manoeuvre. Intraocular pressure was normal, no visual defects were noted,...

Oct/Nov 2016 Quiz

1 October 2016 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 67-year-old female patient had chronic left canaliculitis becoming painful and more recently complicated by left lower blepharitis. Examination revealed a small fleshy lump on the medial aspect of the left lower eyelid. There was also swelling of the...

Apr/May 2014 Quiz 2

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 29-year-old woman presented to the emergency department with a two week history of floaters and patchy peripheral visual field loss in the left eye (LE). She had no relevant medical history and she was not on any current...

Apr/May 2019 Quiz

1 April 2019 | | EYE - General
History A 68-year-old female patient was referred from her GP with bilateral conjunctival lesions on her upper eyelids which cause local irritation and dry eyes. Her past ophthalmic history is uneventful. However, systemically she has history of high blood pressure...