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100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...

Old dogs

It is always nice to get a thank you card, especially so when it comes from someone at the tail end of an overbooked clinic who had waited patiently well past their appointed slot. Such was the case when I...

What's trending Feb/Mar 2025

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ChrisMcCausland #StrictlyWinner “I hope that anybody out there that doesn’t know someone who is blind now has higher expectations of what...

An unusual case of acute retinal necrosis

Case report A 40-year-old Caucasian male presented with a four-day history of redness and progressive painless reduction of vision in the left eye. His visual acuities were 6/4 in the right and 6/36 in the left. The left eye showed...

A case of Miller Fisher Syndrome and bilateral asymmetric globe retraction

Miller Fisher syndrome (MFS) is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It was first recognised by James Collier in 1932 as a clinical triad of ataxia, areflexia and ophthalmoplegia. Later, it...

Papilloedema: an update

Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...

My top five eye-related webinars during lockdown

1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

My Top Five: Eye-related webinars during lockdown

1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

RCOphth 2024 Preview

Here is our annual highlights preview of the upcoming RCOphth 2024 Annual Congress in Belfast's ICC, 20-23 May.

Optic nerve swelling – your survival guide (part 1)

Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

In conversation with Robert F Walters, Orbis Trustee

Can you give us a brief overview of the organisation and its hope for the future? Orbis International is a global non-governmental organisation (NGO) which is dedicated to the prevention of blindness. We’ve now been going since 1982. We’re very...