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Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

The Irlen Experience

My father used to say that humanity is divided into those that see the world through a moral framework and recognise their place within it, and Tories. When a concerned mother came to the paediatric clinic bearing literature from the...

Jury for Fifth Annual Vesalius Innovation Award Announced; Karger Publishers and BMJ Group  Co-presenting

The Vesalius Innovation Award, recognising excellence in science communication, has announced its jury members. This year marks a first in the award’s five-year history, as BMJ Group joins Karger Publishers to co-present the award. The Vesalius Innovation Award for innovation...

Sickle cell maculopathy

This paper reports the result of a prospective study to analyse the prevalence of sickle cell maculopathy (SCM) and its associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity (VA). This study...

In conversation with Robert MacLaren

Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...

Ocular neuromyotonia features

The authors present eight cases of ocular neuromyotonia (ONM) with an overview of the pathophysiology, aetiology, clinical presentations and possible treatments. Diagnosis was made only after thorough and repeated orthoptic examinations and review of medication history. An overview of the...

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Quality of life scores in strabismic children

In this study the authors used the Pediatric Quality of Life Inventory (version 4.0) to evaluate impact of strabismus on health-related quality of life in Portuguese children. This was a prospective study of children aged 5–12 years over a nine-month...

Part 1: The Arclight Project – Frugal tech for sight

Click here for Part 2 on this topic, and here for Part 3 The Arclight Project is a mix of frugal design, manufacturing, distribution, teaching, research, and advocacy, all wrapped up in a social enterprise based at the University of...

Projectors and Stagefright

Choosing the correct aspect ratio for a presentation There are several mistakes that are easy to make when using PowerPoint. The most common one I see is the failure of a video to play because the video file wasn’t copied...

Serendipity

“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...

Blindness from some inherited eye diseases may be caused by gut bacteria

Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.