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Topical insulin for neurotrophic ulcers

This retrospective case series described the use of topical insulin drops as an aid in treatment of refractory neurotrophic corneal ulceration in six patients. Insulin drops were prepared under sterile conditions from standard insulin preparations mixed with artificial tears containing...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

How to achieve 1% solution of Lissamine green

Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...

Ranibizumab for the treatment of age-related macular degeneration

This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...

Biopsy of nasolacrimal duct using sheath guided dacryoendoscopy

In this study the author’s biopsied six eyes of five individuals with recurrent nasolacrimal duct obstruction following a prior dacryoendoscopic probing. All procedures were performed under local anaesthetic, the obstruction or lesion was directly visualised with dacryoendoscope and biopsy was...

Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery

This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...

Amniotic membrane transplantation for SJS/TEN

This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...

Lacrimal drainage system malignancies

This retrospective case series looks at the rare cases of lacrimal drainage system malignancies. The authors have identified 14 patients in 24 years, at a tertiary referral centre in the Indian subcontinent. Many previous publications have found squamous cell carcinoma...

Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery

Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...