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Ophthalmologica journal cover image.

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

3 October 2024 | | EYE - Vitreo-Retinal
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...
Ophthalmologica journal front cover image.

IVT Aflibercept 2mg in nAMD: XTEND at 3 years

3 April 2026 | | EYE - Vitreo-Retinal
This study investigated the long-term, effectiveness and safety of IVT-AFL 2mg for neovascular age-related macular degeneration (nAMD). XTEND was a multicentre, observational, prospective study, which was conducted across 127 centres across 17 countries with a follow-up period of 36 months....
Retina journal front cover image.

Atrophy and anti-VEGF

1 August 2019 | | EYE - Vitreo-Retinal
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...

RPE tears in cases of IPCV

1 April 2020 | | EYE - Vitreo-Retinal
The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...

Beyond 2020: An educational video series from the Amazonian rainforest

3 October 2024 | EYE - Cataract, EYE - Refractive, EYE - Cornea
It has been estimated that one billion people globally live with visual impairment. Moreover, countries in the developing world are disproportionately affected, with four times more low vision than compared to countries with well-established systems of primary, secondary and tertiary...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

1 August 2018 | | EYE - General
Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...

The fragile p-value

5 October 2020 | | EYE - General
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Serendipity

3 October 2024 |
“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...

Andean Medical Mission in action 2025

8 October 2025 | | international, AMM, charity, South America, glaucoma
Dear friends and supporters, What 12 months it has been for the Andean Medical Mission! Thanks to your encouragement and generosity, we’ve been able to continue our work to eliminate avoidable blindness in the Beni region of Bolivia — and...

Interspecialty referrals

4 February 2021 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Strabismus, EYE - Refractive, EYE - Vitreo-Retinal, EYE - General
Referrals between the many and varied branches of ophthalmology sometimes underline how sub-specialised we have all become nowadays. The old era when everyone was an ophthalmic jack of all trades is gone, for better or for worse, and instead of...

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...

My top five eye-related webinars during lockdown

12 August 2020 | | EYE - General
1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...