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Ophthalmologica journal front cover image.

IVT Aflibercept 2mg in nAMD: XTEND at 3 years

3 April 2026 | | EYE - Vitreo-Retinal
This study investigated the long-term, effectiveness and safety of IVT-AFL 2mg for neovascular age-related macular degeneration (nAMD). XTEND was a multicentre, observational, prospective study, which was conducted across 127 centres across 17 countries with a follow-up period of 36 months....
Retina journal front cover image.

Atrophy and anti-VEGF

1 August 2019 | | EYE - Vitreo-Retinal
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
Retina journal front cover image.

RPE tears in cases of IPCV

1 April 2020 | | EYE - Vitreo-Retinal
The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...

Could Twitter boost the impact of ophthalmic journal articles?

1 October 2021 | | EYE - General
*Equally contributing co-first authors. The authors investigate the link between ‘tweets’ and citations for 155 articles from five key ophthalmology journals. Social media’s impact on our lives has been significant, allowing easy discussion of topics worldwide. An increasing number of...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

1 August 2018 | | EYE - General
Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...

The fragile p-value

5 October 2020 | | EYE - General
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Are hospital cataract services managing more complex cases?

5 August 2026 | | EYE - Cataract
An audit of referral pathways and case mix in hospital cataract services. Cataract is the leading cause of irreversible blindness worldwide, causing severe visual impairment, particularly within ageing populations [1]. Gradual lens opacification impairs contrast sensitivity, visual acuity and overall...

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...

My top five eye-related webinars during lockdown

12 August 2020 | | EYE - General
1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

My Top Five: Eye-related webinars during lockdown

12 August 2020 | | EYE - General
1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

Seeing things from down under: Reflecting on an ophthalmology elective in New Zealand

25 September 2026 | | EYE - General
During March 2025, I undertook a four-week elective in ophthalmology at Christchurch Hospital, New Zealand. Having had minimal exposure to ophthalmology within my time at university, I was excited to be further immersed in it whilst also having the opportunity...

Corporate M&A pace gathers momentum

1 October 2019 | | EYE - General
Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...