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Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...

AI detects eye changes that lead to sight loss in young people

Use of Artificial Intelligence (AI) can accurately predict when young people with the sight- threatening eye condition kerataconus need treatment to stabilise the cornea and prevent loss of vision. Developed by researchers at Moorfields Eye Hospital and UCL Institute of...

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Crash Course in Neurology and Ophthalmology (Sixth Edition)

The UK Medical Licensing Assessment (UKMLA) is sat by final year UK medical students and consists of an applied knowledge test (AKT) and a clinical and professional skills assessment (CPSA). This book is tailored to help medical students prepare for...

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

Does vitrectomy increase the risk of glaucoma? A retrospective review from a UK hospital

The authors investigate what proportion of patients undergoing pars plana vitrectomy subsequently developed ocular hypertension or a diagnosis of glaucoma. A systematic review carried out in 2017 including seven studies found that there is evidence that pars plana vitrectomy (PPV)...

The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy

The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

5-FU vs. Avastin as adjunct to conjunctival autograft

The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Achieving post-op target range increases success of strabismus surgery in adults

This is a retrospective cohort study of all patients over 12-years old undergoing strabismus surgery under a single surgeon in a tertiary referral centre in Toronto, Canada. The aim of the study is to determine the role of achieving immediate...

Subthreshold micropulse laser treatment in chronic central serous chorioretinopathy

This retrospective study was conducted to assess the treatment of 38 patients of chronic central serous chorioretinopathy with a 577-nm subthreshold micropulse laser (SML) Supra Scan Quantel Medical. Eighteen patients of these had persistent subretinal fluid (SRF) after photodynamic therapy....

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...