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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Nonarteritic anterior ischaemic optic neuropathy

This review article describes nonarteritic anterior ischaemic optic neuropathy (NAION). This condition is one of the common causes of visual loss in adults. The article uses a good range of references and is divided under the headings of; demographics, clinical...

Functional visual field loss using automated static perimetry

Functional visual field loss is traditionally assessed by kinetic perimetry, typically producing spiralling isopters. This study looked at the spatial distributions of functional field deficits using automated static perimetry. A retrospective review of automated perimetry records was conducted using a...

Three muscle surgery results for ET

There is limited information in the literature on the outcomes of three muscle surgery. The authors aimed to evaluate the medium term motor outcomes of three horizontal muscle surgery in 18 patients with large angle infantile esotropia of at least...

Long-term outcomes for hereditary retinoblastoma

Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...

Fluorescein angiography and OCT in myopic CNV

Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...

IO overaction surgery

This study aimed to compare the effectiveness of two surgical methods on the correction of inferior oblique overaction (IOOA). This was a retrospective study of 99 eyes of 56 patients; 47 myectomy and 52 anterior transposition procedures. Mean age was...

Reduced angle after BT for postop diplopia test

The authors undertook a retrospective study to evaluate the extent of reduced deviation after Botulinum toxin (BT) when used as a postoperative diplopia test. They evaluated effect in 39 patients: 32 exotropia and seven esotropia. The same BT dose was...

Canaloplasty after failed trabeculectomy

The authors describe the technique of canaloplasty performed in five patients who had undergone previous trabeculectomy and under maximum tolerated medical therapy or insufficient intraocular pressure (IOP) control. Canaloplasty is described by the authors as “a nonperforating blebless technique derived...

Long-term outcomes following surgery for traumatic cyclodialysis clefts

This retrospective case series evaluated the long-term visual prognosis and intraocular pressure control following surgical treatment of traumatic cyclodialysis clefts. Cyclodialysis clefts result from the disinsertion of the longitudinal ciliary muscle fibres from the scleral spur and occur as a...

A case report of cavernous sinus syndrome following dental procedure

This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...

Quality of esotropia referrals

The purpose was to examine the quality of referrals made for children with esotropia and to evaluate management offered prior to referral. This retrospective study identified 326 children with esotropia aged less than five years and referred over a period...