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Use of Leflunomide as a treatment for paediatric chronic uveitis
Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...
Ahmed and Baerveldt glaucoma drainage implant outcomes
This study reports the surgical outcomes of both the Ahmed (AGV) and Baerveldt (BGI) glaucoma drainage implants in a cohort of patients with primary congenital glaucoma over a long follow-up in a single tertiary centre. This was a retrospective study...
Repeat corneal collagen cross-linking after failure of primary cross-linking (CXL) in keratoconus
This is a 10-year, retrospective, patients record review from Leeds, UK. Twenty-one eyes had repeated CXL and the mean interval between primary and repeat CXL was 47.1 months. Twenty (95%) eyes stabilised after repeated CXL at a mean follow-up of...
Choroidal changes in multisystem inflammatory syndrome in children
This study aimed to evaluate the vascular structure of the choroid in multisystem inflammatory syndrome in children (MIS-C). This was a prospective study of 38 eyes of 19 patients and 60 eyes of 30 healthy controls. None had ocular pathology....
Medial rectus inferior half plication surgery for near exotropia
In this study the authors report a relatively new surgical treatment for near exotropia. The study included 17 patients: four with previous surgery and all with medial rectus injection of bupivacaine to reduce the angle of deviation. Treatment involved inferior...
Description of surgical modification for heavy eye syndrome
For heavy eye syndrome, these authors report a modification to facilitate approximation of the widely separated muscles using a combination of zip-up and hand-over-hand manoeuvres. Ten patients underwent this surgery with unification of the superior rectus and lateral rectus muscles....
A novel parameter for angle closure
This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...
BT vs primary surgery for infantile esotropia
In this study, the success rate of treatment for infantile esotropia (IET) patients who had surgery because of under correction after botulinum toxin (BT) is compared to those having primary surgery. The study included 52 patients (27 male) with mean...
Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia
This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...
How does teprotumumab impact on ocular misalignment in thyroid eye disease?
A retrospective case review was conducted with the aim of exploring the effect of teprotumumab on objective diplopia. Adults diagnosed with thyroid eye disease, presenting with diplopia and receiving a standard six-month treatment with teprotumumab at a single centre were...
Augmented surgery with BTA for large angle strabismus correction
This retrospective study reports the results of botulinum toxin A (BTA) augmented bilateral recession or monocular recession / resection (RR) for patients with large angle strabismus. Twenty-four patients were recruited: 10 female, mean age 9.2 ±13.6 years, 20 esotropia and...
