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Risk factors for NTG in a young Korean population
Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...
Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Eye drop prescription and usage in glaucoma patients
The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...
Reproducible OCT RNFL map in unilateral glaucoma
The aim of the study was to compare the reproducibility of the optical coherence tomography retinal nerve fibre layer (OCT RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. The authors carried out a prospective case...
Rare case reports of benign optic glioma in adults with clinically aggressive nature
Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...
Do operative interventions for IIH improve visual function?
The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...
Surgical success rates in abducens palsy management
The aim of the study was to identify factors associated with surgical outcomes in isolated abducens palsy. To achieve this goal the authors reviewed the records of adult patients with abducens palsy who underwent strabismus procedures during a fourteen year...
Abducens nerve palsy following surgical correction of craniosynostosis
The authors present two cases of unilateral abducens palsy secondary to a recent trans-sutural distraction osteogenesis (TSuDO) operation for craniosynostosis. The basic principle of the TSuDO procedure is described as dissection and distraction of the prematurely fused sutures. This complication...
Occult spread of squamous cell carcinoma into the orbit
The authors describe two cases that may represent perineural spread of cutaneous squamous cell carcinoma (SCC) into the orbit. Both cases had cutaneous squamous cell carcinomas in the region of the lateral orbital wall (innervated by the zygomatico-temporal nerve) which...
A diagnostic imaging technique for optic pathway tumours
The authors discuss the difficult clinical scenario of patients with deteriorating visual function and an optic pathway lesion. The morbidity associated with biopsy means a highly sensitive and specific imaging technique would be of great value. The authors describe the...
