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Gene therapy: perspectives from young adults with Leber’s congenital amaurosis
The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...Eye research: where next?
Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...
Bioengineered human tissue
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...There will be a 27% rise in the number of people living with sight loss in the UK by 2035, RNIB the UK’s leading sight loss charity predicts
This World Sight Day, leading sight loss charity the Royal National Institute of Blind People (RNIB) was calling for the UK Government to prioritise eye health. This is after fresh insight from the charity that shows there will be a...Retinal sequelae of high voltage electric current injury
Introduction High-voltage electrical currents may result in significant ocular complications, ranging from mild cataracts to vision-threatening retinal and optic nerve problems [1]. The severity of damage depends on various factors, including intensity and type of current, duration of exposure, entry...Blind: Chris McCausland
In the busy, stressful lives that many of us lead, a good way to unwind in the evenings is to watch one of the celebrity panel TV shows such as Would I Lie To You? or Have I Got News...
Nicotine accelerates diabetes induced retinal changes
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
ABCA1 mediates lipid efflux in the retina
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...
Postoperative astigmatism
The authors investigate the short and long-term postoperative refractive effects of medial rectus recession on the involved eye and explain the detectable effects in detail by the results of vector analysis in 52 eyes and 32 patients. The subjects had...
Ocular blood flow changes in Behcet disease
This study evaluates ocular blood flow changes in both ocular Behcets disease (BD) and non-ocular BD (with or without thrombotic disease) and compares these findings with a healthy control group. A total of 90 eyes with BD were evaluated with...
Latanoprost in the treatment of congenital glaucoma
The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...
