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Canadian centre experience with ocular cystinosis cases

Ocular cystinosis (OC) is an uncommon recessive genetic disease occurring in about one case per 100–200,000 live births. Patients have accumulation of cystine crystals within tissues. Ocular symptoms include photophobia, blepharospasm, foreign body sensation, retinopathy and visual impairment. Crystals have...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

High prevalence of strabismus and variable surgical success in children with developmental delay

On the basis of lack of consensus for the treatment of strabismus in children with developmental delay, the authors reviewed the literature to provide information on the topic and present results from their clinical experience. From the review, they include...

Outline of clinical care for healthy newborns with uncomplicated conjunctivitis in the US

The purpose of this study was to explore the current state of clinical care for healthy newborns with uncomplicated ophthalmia neonatorum (ON) using a large electronic health record dataset. Despite the existence of national guidelines for antepartum screening for N....

Prism adaptation responses for variable distance-near deviation in intermittent exotropia

The purpose of this study was to evaluate the effect of the prism adaptation test (PAT) on angle and distance-near-deviation (DND) in intermittent exotropia (IXT), and determine the frequency of responders and non-responders to PAT. This was a single-centre study...

How does presentation, progression and outcome of new onset diplopia vary between older and younger adults?

The authors present a retrospective case review with the aim of comparing the frequency of different causes for new onset binocular diplopia in 2 age groups, above and below 65 years old. Adult patients with new onset diplopia within a...

Clinical outcomes following intraluminal stent removal from the PAUL glaucoma implant

This single German centre retrospective cohort study included 70 eyes from 68 patients. Qualified and complete success rates (95% CI) were 92.9% and 55.7% after 1 year and 88.6% (81.4–95.7%) and 50% (37.1–62.9%) at the last follow-up time point for...

Impact of the Covid-19 pandemic on ophthalmology conferences

The Covid-19 pandemic encouraged the transition to telehealth and virtual platforms in ophthalmology conferences. This cross-sectional study analysed data from five US-based ophthalmology conference organisations. Conference meetings were categorised as in-person, virtual or hybrid. Data included total attendance, trainee participation,...

Selective laser trabeculoplasty after medical treatment

Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...

Opening the AI ‘black box’ for glaucoma

Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...

Risk of fractures with glaucoma

In this systematic review and meta-analysis, 7 articles were analysed, with 570,694 subjects and a reported total of 45,957 fractures. The study protocol (CRD42024527785) was registered prospectively. PubMed, EMBASE, and Web of Science were searched from their inception to April...

Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...