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Review of pathogenesis of Acanthamoeba keratitis
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...The role of artificial intelligence in cataract surgery: An overview
Cataracts are still a leading cause of blindness and, with an ageing population, that burden will only grow [1]. Increasingly experts are leaning on technology such as ‘Surgery 4.0’ [2] – where smart machines and artificial intelligence (AI) slide into...Ophthalmology history and examination – a guide for medical students
*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...Pioneering professor performs 30,000th laser eye procedure
A Moorfields Eye Hospital NHS Foundation Trust and Moorfields Private Hospital consultant has performed his 30,000th refractive laser eye procedure (at Moorfields Private), 36 years after he carried out the first of its kind in the UK. In 1989, while...
Ophthalmology
The textbook is a large, single volume that ideally needs to be desk or table-supported, as its sheer weight makes it virtually impossible to rest comfortably on ones lap. The book is compiled by its two lead authors and editors...Glaucoma patients can monitor and treat their own IOP!
Simerdip Kaur takes a look at the latest ophthalmology-related stories in the news. Headline: Glaucoma patients can monitor and treat their own IOP! It is well known that poorly controlled intraocular pressure (IOP) is a leading risk factor for glaucoma...
5-FU vs. Avastin as adjunct to conjunctival autograft
The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...Cambridge Ophthalmological Symposium 2024: Evolution and the Eye
by Anushka Irodi, Y5 Medical Student, University of Cambridge, UK. The 52nd Cambridge Ophthalmological Symposium, a renowned two-day national meeting, took place on September 5th and 6th, 2024 at St John’s College, Cambridge, UK. It brought together international leading minds...Embryology in clinical practice
The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...
Conventional vs. accelerated cross-linking
The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...
