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2926 results found

Retinal changes in Leber hereditary optic neuropathy

The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...

Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness

The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...

An unusual case of sellar chondroma

A single case of chondrogenic neoplasm arising from the base of the skull is presented and discussed. These benign and slow growing tumours in the sellar region are extremely rare and as such this article provides a useful insight and...

Recognising clinical characteristics of blepharospasm

Focal dystonia is regarded as a characteristic feature of blepharospasm, but patients do not always present with these motor symptoms. The authors present a retrospective analysis of data from a large number of patients treated for drug-induced or essential blepharospasm...

Screening for amblyopia

The purpose was to determine the validity of the OPTEC 5500 vision screener in detecting visual acuity and amblyopia in paediatric patients aged 3-17 years with comparison to the Lea and Snellen tests. This was a cross-section study of 64...

Characteristics of Charles Bonnet syndrome in patients with neovascular AMD

This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...

Amblyopia risk factors detected at screening

The aim of this study was to assess amblyopia prevalence in a population of 299 adolescents aged 10-14 years who were screened for risk factors at pre-school age using photoscreening. Eighty-three had screening at one-year-old, 94 at preschool age and...

Strabismus prevalence in the republic of Moldova

The aim of this study was to assess the prevalence and rate of newly detected manifest strabismus cases in the paediatric population of the Republic of Moldova over 2011-2017. Average coverage of paediatric prophylactic examinations was 60.1% annually – paediatric...

Occult central retinal artery occlusion

Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Test combination which could detect prodromal Alzheimer disease

The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...

Atopic dermatitis: Risk of glaucoma progression?

This population-based retrospective cohort study from December 5, 2003 to December 3, 2018 examined 528,469 patients with glaucoma with a diagnosis of atopic dermatitis (AD) based on diagnostic claim codes from the TriNetX Research Network, which contains real-time information on...