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Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

UKISCRS 47th Annual Congress Preview

Check out the Eye News preview for UKISCRS' 47th Annual Congress in London, 1-3 November.

EEG changes following use of cyclopentolate 1% eye drops

Cycloplegic eye drops may affect the central nervous system. This study reports electroencephalogram (EEG) changes in a cohort of 6–15-year-old children. EEG recordings were taken after placebo and two doses of cyclopentolate 1% in 24 awake children (36 children had...

No risk of dry eye disease in concomitant strabismus cases

This preliminary assessment of the ocular surface of patients with concomitant strabismus before surgery was undertaken to determine if the presence of strabismus increases the risk of dry eye disease. This was a cross-sectional study of 204 patients with concomitant...

Choroidal changes in multisystem inflammatory syndrome in children

This study aimed to evaluate the vascular structure of the choroid in multisystem inflammatory syndrome in children (MIS-C). This was a prospective study of 38 eyes of 19 patients and 60 eyes of 30 healthy controls. None had ocular pathology....

Macular choroidal changes after inferior oblique muscle surgery

This study was undertaken to investigate the retinal neurovasculature, choroidal thickness and choroidal vascular index (CVI) changes at the macula at one week, one- and three-month intervals post inferior oblique muscle myectomy. The hypothesis was that, given the close proximity...

FSAK versus toric IOL implantation for correcting astigmatism in cataract patients

Nine studies of 590 patients were retrieved from the Ovid-Medline, EMBASE, Cochrane register of controlled trials and Scopus which compared femtosecond laser-assisted astigmatic keratotomy (FSAK) and toric IOL for astigmatism correction in cataract patients. The trial sequential analysis was used...

Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists

Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...

Gradenigo syndrome

The authors report four cases of Gradenigo syndrome (GS) with patients aged five to 70 years; three with classic acute presentation and one with presentation of chronic suppurative otitis media, cholesteatoma and sixth nerve palsy. The authors discuss anatomy, neuroimaging,...

Platelet-rich fibrin for conjunctivoplasty after pterygium excision

The authors report a prospective, comparative, non-randomized clinical trial of 35 pterygium patients with unilateral nasal primary pterygium infiltrating the cornea 2-5mm in size, who underwent pterygium excision between June 2013 and September 2014. Thirty-five eyes of 35 patients with...

OCT measures of lateral and medial recti

The authors assessed the agreement of the measurements of the horizontal rectus muscle insertion distance to the limbus and the muscle thickness between three different OCT devices. This was a cross section observation study of 70 eyes of 35 subjects....

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...