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Effect of selenium and vitamin E supplements on the development and progression of cataracts

The Selenium and Vitamin E Cancer Prevention Trial (SELECT) investigated the influence of dietary supplements on the development of prostate cancer in a group of 35,533 middle aged and older, apparently healthy men. The SELECT Eye Endpoint (SEE) study is...

Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support

This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...

Rebamipide 2% for dry eye

Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...

Microvasculature changes of mCNV after ranibizumab treatment using OCTA

In this study the authors aim to evaluate the vascular changes of myopic choroidal neovascularisation (mCNV) after ranibizumab treatment using optical coherence tomography-angiography (OCTA). The 3×3 OCTA en face images were analysed for the absence / presence of mCNV, CNV...

Impact of COVID-19 on primary retinal detachments

This study aimed to describe the impact of the COVID-19 pandemic on the presentation characteristics, timings, and surgical decisions for primary rhegmatogenous retinal detachment (RRD). The cohort included all patients who presented to a Portuguese centre over a two-year period,...

Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients

This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...

Primary visual pathway changes in individuals with chronic mild traumatic brain injury

Patients with mild traumatic brain injury (mTBI) often self-report vision disturbance despite showing no reduction of visual acuity or fundus examination abnormality. This prospective, observational, cross-sectional study aimed to determine if using a sweeping array of investigations can help diagnose...

Scleral fixation using Gore-Tex suture of a subluxated PCIOL

This was a retrospective single-centre study of patients who underwent lasso in-the-bag scleral fixation of a subluxated posterior chamber (PC) intraocular lens (IOL) using the snare technique with Gore-Tex suture from 2019 to 2021. Functional outcome was analysed by clinical...

Changes in ocular biomarkers in Vogt-Koyanagi-Harada disease after pulse steroid therapy

This retrospective study aimed to evaluate the early and chronological changes in ocular biomarkers in patients of Vogt Koyanagi Harada (VKH) disease who received pulse steroid therapy. It further aimed to identify which biomarkers correlated with the best corrected visual...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

Issues with standard practice: Luer lock syringes in cataract surgery

For a few years, we have worked together with the practice variance surveys to tease out differences in the way we work and to discuss issues that arise. I hope that we have learnt some lessons and reflected on what...

Types of nystagmus and associations in a large international database for nystagmus

The authors aimed to characterise a large international cohort of children with nystagmus. Data were taken from a prospective database which was started in 2010. Up to 2020, this contained 1774 patients with nystagmus from 38 US states and 30...