Search

Imiquimod for lentigo maligna

This is a retrospective review of 12 patients with periocular lentigo maligna treated with topical 5% imiquimod cream. In six patients it was the only treatment, and in the other six it was used following partial excision, cryotherapy or both....

Intravenous paracetamol in orbital surgery

This is a large prospective study of the effect of intravenous acetaminophen (paracetamol) in orbital surgery. The study included three groups of 50 patients. One group had no i.v. paracetamol, the second 1g of i.v. paracetamol within 30 minutes of...

Sliding lower lid tarsal flap

This is a retrospective review of a lower lid reconstructive technique utilising a sliding tarsal flap. Thirty-two patients who had undergone Mohs surgery were included and each had a shallow marginal defect with at least one remaining tarsal edge having...

Prophylaxis for clinical macular oedema after phacoemulsification

The authors report on a retrospective cohort study looking at three different prophylaxis methods for macular oedema after cataract surgery: 1) Topical prednisolone acetate (PA) alone; 2) Topical PA in combination with non-steroidal anti-inflammatory drug (NSAID); 3) Intraoperative subconjunctival injection...

DALK as an early therapeutic option for Acanthamoeba keratitis

Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

Familial Mediterranean Fever and keratoconus

This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...

How to achieve 1% solution of Lissamine green

Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...

Confocal microscopy and corneal graft rejection

Forty-five patients following penetrating keratoplasty (PK) were examined with the HRT III Rostock Cornea Module confocal microscope at various points after their surgery for two years. Activated keratocytes (AKs) were counted manually and their mean number evaluated. A pattern was...

Anterior segment OCT predicts gonioscopic angle closure

This is a prospective observational study of 342 subjects over four years. Sixty-five were controls who had open angles both on gonioscopy and AS-OCT, while 277 had open angles only on gonioscopy but iridotrabecular contact (ITC) on AS-OCT (one to...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

Amiodarone-associated optic neuropathy

This is a retrospective population-based cohort study to evaluate the risk of developing optic neuropathy from the use of amiodarone in Taiwan. Over a five-year period (2005-2009), there were 6175 amiodarone-treated patients with 24,700 patients taken as controls. After a...

A rare case of ophthalmic complications following allergic fungal sinusitis

The authors present an unusual case report of a 32-year-old man with advanced allergic fungal sinusitis, presenting with severe bilateral visual loss and restricted ocular motility. On presentation he had an 18 month history of progressive nasal obstruction, as well...