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Association between serum triglycerides and pan retinal photocoagulation in type 1 diabetes
This retrospective cohort study aimed to examine whether dyslipidaemia is a risk factor for progressing to proliferative diabetic retinopathy (PDR) and consequently requiring pan retinal photocoagulation (PRP) treatment in type 1 diabetics. In previous studies including the ETDRS study an...
Atrophy and anti-VEGF
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
PRPF31-related retinitis pigmentosa and asymptomatic carriers
The authors present a study of 21 patients with variants in the PRPF31 gene classified as pathogenic or likely pathogenic. These variants are caused by autosomal dominant retinitis pigmentosa (RP-11). Between January 2020 and November 2021 patients underwent tests of...
Reproductive counselling for females with X-linked inherited retinal diseases
The authors report a survey-based study of 118 female patients who were genetically confirmed carriers or obligate carriers of an X-linked inherited retinal disease. The majority (66.9%) of these patients were carriers of choroideremia; other diagnoses included retinitis pigmentosa, X-linked...
Ethnic disparities in diagnostic sequencing yield
The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....Heidelberg Engineering Celebrates Eye2Gene™ AI Breakthrough in Precision Ophthalmology
Heidelberg Engineering proudly announces a significant advance in the use of artificial intelligence for ophthalmic diagnostics, with the publication of the Eye2Gene™ study in Nature Machine Intelligence. Titled “Next-generation phenotyping of inherited retinal diseases from multimodal imaging with Eye2Gene”, the...
Recommendation for wide angle fluorescein angiography to diagnose FEVR in NEDSDV
Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV) is a genetic disease described in 2012 associated with variants in the CTNNB1 gene which encodes beta-catenin. Characteristics include strabismus, reduced visual acuity and familial exudative retinopathy (FEVR). In this study,...iCare EIDON: Redefining TrueColor Confocal Retinal Imaging for Modern Eye Care
The iCare EIDON is the next-generation confocal fundus imaging system designed to deliver exceptional TrueColor retinal images with outstanding clarity, depth, and diagnostic precision. Combining a full-spectrum white LED light source with confocal scanning technology, it produces images that closely...Behind the curtain: What trainees wish they knew before starting in ophthalmology
As a foundation year doctor, I didn’t expect ophthalmology to feature much in acute medicine or surgery. Yet it kept appearing at the periphery – and when it did, it was often complex and unexpectedly urgent. A confused older patient...Landmark dataset to accelerate research on anterior segment eye disease
Diseases affecting the anterior segment, the front part of the eye, are among the leading causes of visual impairment and blindness globally, yet few large-scale datasets have been available for these conditions. In response, clinical researchers at Moorfields Eye Hospital...
Intermittent exotropia and refractive change in children
The authors present a retrospective case review with the aim of examining the relationship between refractive change and intermittent exotropia (IXT). The medical records of patients were reviewed for those aged 18 years old and younger diagnosed with IXT with...
