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Microvascular disease in Alport syndrome

The authors present the findings of a retrospective case-control observational study on increased microvascular disease in individuals with Alport syndrome recruited over a 21-year period. They recruited 28 males and 28 females with X-linked Alport syndrome (XLAS) and eight men...

Near-infrared autofluorescence to diagnose retinal laser injuries

This retrospective observational case series aimed to assess whether near infrared autofluorescence (NIR-AR) imaging is a useful imaging modality in the diagnosis of hand-held laser retinal injuries. Twelve patients from two centres underwent ophthalmic assessment and retinal imaging including fundus...

Wet AMD outcomes post cataract surgery

The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...

Inflammation and microvascular changes in diabetic retinopathy

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...

Effect of alcohol dependency on visual function

The purpose of this study was to evaluate visual function, attention and psychological profiles in consumer and abstainer alcohol dependency syndrome (ADS) patients in a Portuguese population. The study was a quantitative, descriptive, cross-sectional and correlational study over a one-year...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

OCT changes after occlusion therapy in amblyopic and fellow eyes

This study compared optical coherence tomography (OCT) data of fellow and amblyopic eyes, and reported OCT changes after long-term electronically monitored occlusion therapy. The study recruited 30 patients with mean age of 16.7 ±11.2 years (range 5.1–44.7 years): 53% males....