You searched for "regulation"
Ovarian hormones drive onset of Sjogren’s disease in mice
1 December 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Providing primary eyecare services during a global pandemic: the new normal
7 December 2020
| Janet Pooley
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EYE - General
It would be fair to say that 2020 hasn’t quite turned out to be the year that anyone predicted. Living with a global pandemic has become our reality and we are having to get used to many aspects of our...
Protecting retinal ganglion cells
1 August 2017
| Sofia Rokerya
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EYE - Glaucoma
Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...
AOP responds to GOC consultation on contact lens care
The regulator is reviewing the process for verifying contact lens specifications and the definition of patient aftercare.Complement Factor H and Factor H-Like protein are expressed in human RPE cells
1 April 2014
| Bheemanagouda Patil
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EYE - General
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
Sustainability in eyecare: Intraocular gases and the climate emergency
In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...AOP welcomes focus on improved patient outcomes in Pharmacy Supervision Review Group report
Recommendations review legislative framework for the future delivery of pharmacy.An introduction to research governance
1 February 2014
| Nana Theodorou
Research is the process of acquiring new generalisable knowledge and should be fully integrated into health care work. There is a growing drive to encourage and further develop evidence-based practice in ophthalmology so that staff and patients benefit from improved...
EyeSi Simulation: a cutting-edge training tool for doctors
As the medical field continues to evolve, so does the need for innovative and effective training methods for doctors. One such advancement in medical education is the EyeSi simulation.Requirements guidance issued as optometry contract for Wales comes into force
Optometry Wales outlines new rules for practitioners practising in Wales.γδ T cell depletion does not affect fungal keratitis
1 August 2015
| Graham Wallace
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EYE - Cornea, EYE - General
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CFW, Cytokines, FK, Fungal keratitis, IL-17, Neutrophils, calcofluor WHITE, fungal keratitis, γδ T cells
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
5 June 2023
| Rod McNeil
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...