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WVUK (Women in Vision) Winter Meeting 2023

12 December 2023
December 2, 2022, brought together Women in Vision UK (WVUK) members for their winter meeting. WVUK is a membership organisation focussed on gender equality in vision-related sciences and healthcare. This year’s winter meeting was held in Moorfields Education Hub and...
Seminars in Ophthalmology journal cover image

Intravitreal Ziv-Aflibercept: safety analysis

7 December 2020 | | EYE - Vitreo-Retinal
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Image of an eye for top of web page.

Ophthalmic DOPS and OSATS: The Handbook for Work-Based Assessments

1 October 2015 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - General, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
The first thing to say is: “I wish I’d had this book when I was an ST1!” The number of work-based assessments (WBA) required during ophthalmic specialist training (OST) is a daunting prospect to trainee ophthalmologists, particularly ST1s with no...

Comparison of corneal deformation parameters in keratoconic and normal eyes

1 February 2018 | | EYE - Cataract, EYE - Refractive
This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...

A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

1 February 2016 | | EYE - Vitreo-Retinal
This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

PRN Ranibizumab verses continuous aflibercept in UK clinical practice

1 October 2018 | | EYE - Vitreo-Retinal
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...

Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome

1 October 2015 | | EYE - Cornea, EYE - General
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Treatment for cause of sudden sight loss now available through the NHS in England

24 September 2025 | LHON, NICE, vision Loss, mitochondrial disease, NHS England
The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

NICE approves treatment for cause of sudden sight loss

15 October 2025 | genetics, neuro-ophthalmology, drugs, new treatments, mitochondrial
The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

Third nerve palsy

1 August 2017 | EYE - Neuro-ophthalmology, EYE - General
Case scenarios A 71-year-old female presented to a nearby eye emergency unit with two days history of partial ptosis in her left eye with diplopia. She saw her GP earlier that day and he asked her to go to the...

Comic leaflets: an innovative method of patient education

1 August 2014 | | EYE - General
Nowadays almost everyone has been exposed to comics, especially during childhood. In a way, this is a natural form of progression from children’s story books, which also contain words and pictures. This exposure has helped us to develop the graphic...