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Canadian centre experience with ocular cystinosis cases

Ocular cystinosis (OC) is an uncommon recessive genetic disease occurring in about one case per 100–200,000 live births. Patients have accumulation of cystine crystals within tissues. Ocular symptoms include photophobia, blepharospasm, foreign body sensation, retinopathy and visual impairment. Crystals have...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis

This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...

Touching base with Peter Holland, CEO of the IAPB

For the upcoming Eye News Dec/Jan 2025, our co-editor, David Lockington, had the opportunity to sit down with the CEO of IAPB, Peter Holland. We’re really excited to share this interview with you, which delves into Peter’s fascinating career and...

Oct/Nov 2014 Quiz

History 12-year-old cattle herder in Bangladesh. Loss of vision right eye – over 2/12 to no perception of light (NPL). B-scan showed choroidal thickening. Suspected to be choroidal ‘tumour’. Enucleated. Figure 1. Figure 2. Figure 3. Figure 4. Figure 5....

Third nerve palsy

Case scenarios A 71-year-old female presented to a nearby eye emergency unit with two days history of partial ptosis in her left eye with diplopia. She saw her GP earlier that day and he asked her to go to the...

Disseminated cutaneous zoster – a masquerade

Reactivation of varicella zoster infection in the elderly commonly presents to ophthalmologists as herpes zoster ophthalmicus (HZO), affecting the Va trigeminal dermatome. In patients with impaired immunity, zoster infection occurs with increased severity and may be complicated by visceral and...

A refractive surprise after vitrectomy and capsulectomy

Figure 1: Right posterior capsule small aperture. We report a case of a pseudophakic patient who underwent vitrectomy and posterior capsulectomy. In spite of good visual acuity and absence of floaters, he was unhappy with the visual outcome. Case report...

Blurred vision post liver transplant: to blame the house cat or not?

This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

Choroidal melanoma – breaking bad news

Case report A 55-year-old Caucasian female presented to her general practitioner with a three-month history of headaches and worsening blurred vision in the left eye. On further close questioning, she reported no eye pain, intermittent floaters and flashes of light...

Usefulness of gonioscopy to investigate cause of corneal oedema after cataract surgery

A 72-year-old man with ocular hypertension presented three months after routine right phacoemulsification and toric intraocular lens (IOL) implantation with a two-week history of an irritated right eye and a sudden deterioration in right vision. His preoperative spherical equivalence was...

Burning vision: vision loss from misuse of ‘toy’ laser pens in children

A case series of five children with macular burns due to the misuse of novelty laser products, purchased online or abroad, was undertaken at the Royal Hallamshire Hospital and The Children’s Hospital, Sheffield [1]. All patients were from the Sheffield...