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Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

OCULUS supports the 23rd German Down Syndrome Sports Festival in Wetzlar

Once again, OCULUS brought the 'Vision Olympics' to the German Down Syndrome Sports Festival in Wetzlar. Participants had the opportunity to have their vision tested and receive a brief screening of the anterior segment of their eyes. This year, the...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

Outline of clinical care for healthy newborns with uncomplicated conjunctivitis in the US

The purpose of this study was to explore the current state of clinical care for healthy newborns with uncomplicated ophthalmia neonatorum (ON) using a large electronic health record dataset. Despite the existence of national guidelines for antepartum screening for N....

Prism adaptation responses for variable distance-near deviation in intermittent exotropia

The purpose of this study was to evaluate the effect of the prism adaptation test (PAT) on angle and distance-near-deviation (DND) in intermittent exotropia (IXT), and determine the frequency of responders and non-responders to PAT. This was a single-centre study...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

Implications of missed foreign bodies under the upper eyelid

Children aren’t the best historians. As a result, clinicians sometimes rely on the accounts of parents regarding problems. Missed foreign bodies due to poor histories or incomplete examinations may result in irreversible loss of vision. This case report shines light...

The paediatric cataract: an overview of the embryology and pathophysiology

In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

An eyeful of independence

Scots will decide this September whether or not Scotland should be an independent sovereign state. “As all key areas of our business are already fully devolved, it’s very much business as usual for us,” noted a spokesperson for Healthcare Improvement...

What's trending Aug/Sep 2021

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #algae #optogenetics Scientists in Paris have used optogenetics to partially restore sight in a blind man’s eye who was diagnosed with...

Bovine pericardium scleral patch graft associated scleritis: Ahmed valve implant for pupillary block glaucoma

Processed bovine pericardium is a lyophilised collagen sheet used as a surgical armamentarium. It renders the material antigenically inert with minimal inflammation [1]. Sclera patch pericardium graft (Tutopatch) is a collagenous membrane derived from solvent preserved, irradiated bovine pericardium [2]...

A near miss

A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...