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Sensitive cilia – eyelashes in health and disease

5 October 2020 | | EYE - Cornea, EYE - Orbit, EYE - Oculoplastic, EYE - General
In health our eyelashes protect the eyes, but in disease they can disfigure, impair quality of life and threaten vision. In this review the authors discuss aspects of lashes that are relevant to all professionals working near the eyes and...

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

4 February 2025 | | EYE - Oculoplastic, EYE - Orbit, EYE - Pathology
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...

Typical or surprisingly uncharacteristic presentations of neuro-ophthalmic emergencies

1 April 2019 | | EYE - Neuro-ophthalmology, EYE - General
Irrespective of geographical location or patient cohort, emergency departments are high risk locations capable of inspiring extreme anxiety and dread in patients and doctors alike. The stress multiplies when a walk-in or referred case is suspected of underlying neurological pathology....

Idiopathic intracranial hypertension (IIH)

3 June 2021 | | EYE - Neuro-ophthalmology, EYE - General
IIH is a medical condition where the intracranial pressure (ICP) is raised without an obvious cause. The cerebrospinal fluid (CSF) is produced in by the choroid plexus in the lateral ventricles and the roof of the third and fourth ventricles,...

A case of congenital lacrimal fistula: an overview of diagnosis and management

1 June 2022 | | EYE - Paediatrics, EYE - Strabismus, EYE - General
Shivam Goyal and Kyaw Htun Aye describe the challenges of dealing with a rare case of congenitial lacrimal fistula.We present a case of a 19-month-old baby with a congenital abnormality. Congenital lacrimal fistulae are a spot diagnosis due to its...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

The TOPCON / OIA Imaging Competition and a brief history of ophthalmic photography

3 June 2021 | | EYE - Imaging, EYE - General
We hope you like and appreciate the image forming the cover of the June/July 2021 edition of Eye News. The Ophthalmic Imaging Association (OIA) was honoured to have been invited to submit a series of images from the winners of...

Non-infectious Uveitis: Well Known, Weird and Wonderful meets You, Me and the Balloons

3 August 2023 | | EYE - Vitreo-Retinal
Installation view from Manchester International Festival 2023 exhibition Yayoi Kusama: You, Me and the Balloons at Aviva Studios. Images © David Levene. On an uncharacteristically salubrious 5 July 2023, the date of the 75th Anniversary of the UK’s NHS, a...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Non-organic visual loss

2 December 2019 | | EYE - Neuro-ophthalmology, EYE - General
Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...

Childhood glaucoma

2 October 2025 | | EYE - Paediatrics, EYE - Glaucoma
When a child is given a diagnosis of glaucoma, the impact upon that child and their family is enormous; equivalent to the diagnosis of a cancer [14]. This previously published article (2019) outlines the knowledge, techniques and approaches that offer...

Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...