Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...
It is now nine months since the full-scale Russian invasion of Ukraine commenced in late February 2022, with Putin announcing a “special military operation” to “denazify and demilitarise” Ukraine. The rest of the world, however, saw it for what it...
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...
This study aimed to determine the efficacy of the Shin-Nippon NVision-K5001 autorefractometer using the open-field refractometry principle in the elimination of accommodation in children. One hundred and fourteen patients aged three to six years were recruited. After excluding ocular pathology...
The purpose of this study was to determine whether providing access to instrument-based screening equipment would increase the total number of high quality age-appropriate vision screenings provided to pre-school aged children. SPOT vision screening was placed in paediatric offices at...
The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...
In a recent discussion with colleagues, someone recognised that many, when asked what they do, say, “I am a doctor”. Rather than “I work as a doctor”. This sense of belonging, pride and duty comes with responsibility. Becoming a surgeon,...
Ann-Marie Ablett is a Theatre Nurse and Team Leader who volunteers with Orbis. This has allowed her to gain a wealth of experience on ophthalmic procedures, nursing in under-privileged parts of the world, leadership, management and use of scarce resources....
A new set of data protection regulations became law in the EU (including the UK) in May 2018. General Data Protection Regulation (GDPR) replaces the 1988 Data Protection Act. The regulation brings new rights and expectations about how our personal...
The purpose of this study was to measure postoperative agitation using a standardised scale and evaluate whether it is reduced if given clonidine prior to strabismus surgery as compared to placebo. The scales included the Pediatric Anesthesia Emergence Delirium (PAED)...
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
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