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My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

The results of the last survey Feb22

1 February 2022 | | EYE - Cataract, EYE - Refractive, EYE - General
This edition’s survey took a slightly different tack and tried to look at the problems we face in litigation. Litigation is unpleasant. It is horrible being involved in it and the process of litigation can be extremely stressful. From the...

Ophthalmology Specialty Training 2024: What's different?

13 December 2023 | | EYE - General
The 2024 intake for ophthalmology specialty training (OST) has undergone several significant changes in its approach towards candidate selection and assessment. This article provides a comparative analysis, detailing these new measures and comparing them against the previous year's standards. Our...

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

5 October 2020 | | EYE - Glaucoma, EYE - General
Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....

How to write and publish a case report – tips and common pitfalls

2 August 2024 | | EYE - General
Ophthalmology is an extremely popular specialty, with the competition ratio at ST1 level entry being 10:1 in 2023 [1]. Consequently, applicants are required to achieve higher portfolio scores to remain competitive. For those considering a career in ophthalmology, two points...

In conversation with Robert Henderson

14 November 2024 | EYE - Imaging, EYE - Paediatrics, EYE - Vitreo-Retinal
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

1 April 2016 | | EYE - General
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Trans-sinus endoscopic removal of retrobulbar air gun pellet within the orbital apex

2 August 2022 | | EYE - Orbit, EYE - General
Injuries to the eye have been widely reported in medical literature due to a variety of mechanisms causing significant morbidity and occasional unexpected mortality for the patient [1]. It is often wrongly assumed that air gun pellets lack this potential....

Zeiss field machines, public Wi-Fi risks and IoT scanning

1 April 2017 | | EYE - Imaging
End of support for old field machines Zeiss have recently announced that they are withdrawing support contracts for many of their older 7 series Humphrey Field Analysers (HFAs) in November 2017. They have confirmed maintenance contracts can continue, but repairs...

How to pass the FRCOphth part 2 written

1 February 2022 | | EYE - General
The part 2 written exam comprises of 180 multiple choice questions – spread over two 120-minute sessions. According to the most recent college exam reports, the pass rate ranged from 45 to 70% in 2019/2020. Most trainees seem to sit...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

1 October 2015 | | EYE - Vitreo-Retinal
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Uveal melanoma

3 August 2023 | | EYE - Pathology, EYE - Oncology, EYE - Imaging
Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...