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Aflibercept (AF) for age-related macular degeneration (ARMD): four-year outcomes of a ‘’treat-and-extend’ (T&E) regimen with exit-strategy
This is a retrospective observational study of 82 patients, between 2014 to 2016 from Switzerland of treatment-naive patients with nARMD, treated with AF, with specific T&E protocol without a loading phase and predefined exit criteria and patients were observed three...
Outcomes of combined medial and laser treatment for advanced Coat’s disease
In this study, the anatomical and visual outcomes of paediatric patients with advanced stage 3+ Coat’s disease are reported. Patients were treated with a combination of intravitreal ranibizumab, laser photocoagulation and methyl prednisolone acetate. This was a retrospective review of...
Outcomes from evisceration with primary implant in 1800 patients
This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...
Saccadic measurements in intermittent exotropia vs fusional amplitude
The authors investigated the correlation between fusional convergence amplitude and saccades during the shift from exotropia to binocular fixation during the cover / uncover test. This was an observational study of 15 patients (six female, nine male) with intermittent exotropia....
Bromfenac versus betamethasone in diabetic macular oedema
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...
Prismatic contact lens correction vs prismatic glasses
The aim of this study was to verify if diplopia could be corrected by applying soft directional prism contact lenses, to compare effectiveness of diplopia correction, comfort and quality of vision with these contact lenses compared to prism glasses. This...
Retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis
Rhino-orbital-cerebral mucormycosis (ROCM) is a rare and often fatal infection usually occurring in immunocompromised patients from diseases such as diabetes, haematological malignancy and solid organ transplantation. Current standards of care include systemic antifungal therapy and debridement, including exenteration. This study...
Congenital nasolacrimal duct obstruction in patients with craniofacial abnormalities
This is a retrospective study including 1998 patients over a period of 10 years. Of this number, 41 patients were identified as having a craniofacial abnormality and congenital nasolacrimal duct obstruction (CNLDO) (23.1 per 10,000 live births). Interestingly the most...
Treatment for chronic severe bilateral blepharokeratoconjunctivitis
This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...
