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Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
ARN in North Africa
Acute retinal necrosis (ARN) is a rare cause of uveitis. This paper aims to outline the clinical features of 12 patients with ARN in a referral centre in Tunisia, North Africa. A retrospective review of case notes was carried out....
Oral omega-3 fatty acid treatment for dry eye in contact lens wearers
This study evaluates the effect of dietary omega-3 fatty acid supplementation of dry eye symptoms, tear film tests, and conjunctival impression cytology in patients with contact lens wear-associated dry eye. In this randomised double-blind, multi-centred trial, contact lens wearers (n=...
Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma
Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...
The dynamic nature of orbital cavernous haemangiomas
This paper seeks to address the question of how much do orbital cavernous haemangiomas actually change over time, and if there are any identifiable factors which can predict which lesions will grow and which will remain stable. In particular, if...
Management of diffuse OSSN with topical chemotherapy
Ocular surface squamous neoplasia (OSSN) can be localised to the conjunctiva or, less commonly, diffusely spread over the conjunctiva and cornea. Localised OSSN can be treated by surgical removal with adjuvant cryotherapy and chemotherapy with low rates of recurrence. Diffuse...
Effect of anti-VEGF treatment on PED morphology
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Avoiding pre-placed recti sutures in enucleation
This is a retrospective review of 40 patients who underwent enucleation using a non-conventional technique in which the recti muscles were detached from the sclera without pre-placing any sutures to secure the cut muscle ends. The surgery was only performed...
Adjunctive topical 5-FU vs. MMC for surgically excised, localised OSSN
Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive OSSN has been surgical excision with or without intraoperative cryotherapy. Postoperative adjunctive topical chemotherapy significantly...
Non-arteritic anterior ischaemic optic neuropathy in the Asian population
This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...
Long-term corneal crosslinking results in paediatric eyes
This prospective longitudinal study examined patients 18 years of age or less with progressive keratoconus, who underwent corneal crosslinking and completed 10 years of follow-up. Crosslinking protocol involved removal of epithelium, 10 minutes of riboflavin soaking, followed by 30 minutes...
