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The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

Optic nerve swelling – your survival guide (part 2)

In this second article we will discuss bilateral optic nerve swelling, its aetiology, various investigations and possible treatments. We will also discuss various protocols used in the management of suspected optic nerve swelling cases. (Part one of this topic available...

In conversation with Robert Henderson

Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...

Retinopathy of prematurity

This review article describes the pathophysiology of retinopathy of prematurity (ROP). The authors start by introducing the condition and its incidence. There is extensive information on the pathophysiology mechanisms involved in the condition to include normal and pathological retinal development....

Correlation between peak intraocular pressure following water drinking test and pulsed methylprednisolone therapy

Steroids have long been known to cause increased intraocular pressures (IOP) in susceptible patients. Intravenous methylprednisolone is used to treat many rheumatological conditions and one of the risks is raised intraocular pressure. It would be useful to find patients at...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Best way to detect glaucoma progression: by reflecting on the past 25 years

Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...

Quiz Apr/May 2023

History A 76-year-old female presented at her local district general hospital with right decreased visual acuity, glare, and foreign body sensation, in addition to longer-term dry eyes. She was otherwise well. Her past medical history included hypertension. On examination: vision...

Developments in retinal pigmentation measurement and the hopes of an equitable future

Our AI & Oculomics co-editor, Nima Ghadiri, sat down with Abraham Olvera-Barrios from Moorfields and Anand Rajesh from the University of Washington to discuss their recent international study into retinal pigmentation and its wider clinical, technological and academic applications. Can...

Papilloedema: an update

Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...

The curse of the college museum

David Greig lecture notebook. Courtesy of Dr Jacqueline Cahif, College Archivist, Royal College of Surgeons of Edinburgh. As sure as the inevitability of death and taxes, the hidden stories of past events will intermittently rise to the surface like oil...