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New Moorfields stem cell treatment improves vision for untreatable condition

A new breakthrough stem cell treatment for ARK (aniridia-related keratopathy) has seen patients’ vision improve for this previously untreatable rare genetic eye condition in a first-in-human clinical trial at Moorfields Eye Hospital and the UCL Institute of Ophthalmology, published in...

Comparing femtosecond laser assisted-DMEK to manual DMEK

Femtosecond laser is as a novel tool for performing precise descemetorhexis in descemet membrane endothelial keratoplasty (DMEK) surgery. In DMEK surgery, the recipient’s Descemet membrane is peeled to allow adherence of the donor DMEK tissue to the recipient’s stroma. Complete...

Nurse-led Rapid Corneal Collagen Cross-linking / UKISOP Society Education Day

Nurse-led Rapid Corneal Collagen Cross-linking By Dan Gore Over the last decade, clinical trial data has accumulated for new interventions in keratoconus that promise to arrest disease progression, significantly reduce transplantation rates and save many patients from long-term reliance on...

Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Conservative vs surgical management outcomes for congenital fibrovascular pupillary membrane for young vs older children

The authors present the clinical characteristics and outcomes of different treatment methods for congenital fibrovascular pupillary membrane (CFPM). This was a retrospective case series from a single centre including 12 patients (13 eyes; 4 males, 8 females) over a 7-year...

Normative data values for childhood corneal sensitivity

The authors aimed to establish normative data regarding corneal sensitivity in a paediatric age group. They included 122 right eyes of 122 children with mean age of 11.29 ±4.6 years (aged 5–18 years); 63 female and 59 male. Bilateral corneal...

Life’s rich tapestry

Have you ever watched someone cross-stitch, or do needle-point? I recently had the joy of observing my teenage daughter create such an artwork. She separated all the threads into the various colours, and then started to follow the instructions carefully....

Combined PRK and CXL in keratoconus

This study aimed to investigate the results after photorefractive keratectomy (PRK) followed immediately by standard 30-minute corneal cross-linking (CXL) for keratoconus. This retrospective study included 26 eyes of 16 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual...

Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula

Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...

Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

Astigmatism correction in cataract surgery: Why are we still hesitating?

Toric spectacle lenses were first described in 1847 by George Biddell Airy, and their adoption was, presumably, gradual at that time. Today, correction of astigmatism with glasses is routine. In a recent survey, 87.2% of spectacle prescriptions contained at least...

Quiz Dec/Jan 2023

History A 35-year-old female presented to the emergency eye clinic with an acutely red, painful, photophobic left eye. She was a contact lens-wearer but denied swimming, showering, or sleeping in her lenses. She resided on a farm and worked as...