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A revolution in modern genetic testing for the clinical management of ocular disease
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...
Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders
This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...NHS Practitioner Health: Providing you with the care you deserve
Healthcare professionals carry a unique weight: the responsibility for the lives and wellbeing of others. But who takes care of the caregivers? For over 15 years, NHS Practitioner Health has been doing just that – providing vital mental health and...NHS England - PCSE online business continuity plan
In advance of paperless claims and payments for GOS, NHS England publishes updated business continuity plan as a failsafe in instances when there is a PCSE system outage or connectivity issues.
Nanofiber-based hydrogels prevent capsular opacification
Lens refilling is the replacement of the lens with a silicone polymer in an otherwise intact lens capsule. However, capsular opacification (CO), resulting in reduced visual acuity, is a major complication of these injectable accommodating lenses. Opacification is due to...
Botulinum toxin after orbicularis myectomy
This is a retrospective review of 27 patients with benign essential blepharospasm who had become resistant to treatment with botulinum toxin and had therefore undergone orbicularis myectomy of the upper lids. The study compares the dose and frequency of botulinum...
Do operative interventions for IIH improve visual function?
The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...
Vici syndrome
Vici syndrome is a condition associated with agenesis of the corpus callosum, congenital cataract, incomplete albinism, ± immunodeficiency and cardiomyopathy. Individuals show profound hypotony and severe neuro abnormalities. This paper reports a case of Vici syndrome. A 38-month-old female had...
Assessing the quality of scars from incisions made by a Colorado needle or a scalpel
Traditional teaching has held the best scars are achieved with cold steel although no previous study has formally investigated this hypothesis in oculoplastic surgery. This paper describes a non-randomised cross-sectional study comparing the scar quality achieved from cold steel with...
Acute dacryocystic retention
This is a retrospective study of patients with acute dacryocystic retention (ADR). The condition is distinct from infectious dacryocystitis, and is characterised by an acute onset of pain and epiphora associated with a tender but not inflamed lacrimal sac thought...
Chronic drop use and trabeculectomy on tear osmolarity
Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...
