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A novel computerised portable pupillometer detects and quantifies relative afferent pupillary defect
1 February 2016
| Jonathan CP Roos
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EYE - Neuro-ophthalmology
We have all had referrals from A&E telling us that a patient can’t see out of one eye. Sleepily we may ask “Is there an relative afferent pupillary defect (RAPD)?” to evaluate the seriousness of the presentation. The response is...
Facilitators and barriers to conducting research
A survey of clinicians and researchers across the UK was conducted to identify barriers to research and potential solutions. The authors extracted details of studies listed on the UKCRN database that involved paediatric ophthalmology with recruitment of children. An e-survey...Are retinal vein occlusions seasonal? And if so why might that be?
1 June 2015
| Jonathan CP Roos
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EYE - Vitreo-Retinal
Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...
Ovarian hormones drive onset of Sjogren’s disease in mice
1 December 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Macular thickness and visual fields
1 April 2014
| Lorraine North
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EYE - Glaucoma
The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...
Multimodal imaging in wet AMD
1 April 2019
| Saruban Pasu
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EYE - Vitreo-Retinal
This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...
Mini DMEK for acute hydrops
This is a retrospective analysis of three patients who underwent mini DMEK for massive corneal hydrops in acute keratoconus. DMEK graft was trephined or trimmed according to the size and the shape of the gap in the patient’s Descemet membrane...Questionable ERG use for Vigabatrin screening
The authors aimed to identify the usefulness of electroretinograms (ERGs) as screening for retinal toxicity in patients taking Vigabatrin in a single centre study. This was a retrospective review of full field ERGs and included 170 ERGs of 138 patients...Review of international telemedicine infrastructure for ROP
This review aimed to review the information and communications technology available for telemedicine, the internet access and economic status of countries at greater risk for higher prevalence of ROP, the framework of established ROP telemedicine programmes, and the cost-effectiveness of...Can a dose scale be calculated for the modified Harado-Ito procedure?
3 February 2023
| Fiona Rowe (Prof)
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Harada-ito procedure, cyclodeviation, fusion evaluation, synoptophore, torsional diplopia
The aim of this study was to review the surgical outcomes of the Fells modified Harado-Ito procedure using a dose scale approach with long-term follow-up, and to evaluate the relationship between preoperative factors and final outcome. This was a retrospective...
Use of Strabocheck to measure angle of deviation
Strabocheck (SK) is a free to access software and is a measurement of deviation angle based on the corneal light reflex in monocular and binocular photographs uploaded to the website. The purpose of this study was to evaluate SK in...Junior doctors in emergency departments lack confidence when managing ophthalmic emergencies
30 January 2025
| James Kirkpatrick
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EYE - Cornea
This systematic review assessed the confidence of doctors in the UK working in emergency departments (EDs) to manage ophthalmic emergencies, with secondary outcomes looking at doctor’s confidence in performing fundoscopy and using the slit-lamp, and training received in the ED....