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Fenofibrate and diabetic retinopathy

Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...

Here comes the fear

“At a cardiac arrest, the first procedure is to take your own pulse” The quote above is the Fat Man’s third law from the book The House of God by Samuel Shem, previously described in the ‘Doctor by the sea’...

Could the sclera be key to glaucoma?

The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...

William’s Marathon Mission: Running for Sofie and Sight Scotland

William Oviatt is running the Edinburgh Marathon to raise money for Sight Scotland to say thank you for all the help and support the charity gave to his family when his daughter, Sofie, was diagnosed with retinal dystrophy.

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

AOP welcomes report calling for redirection of future funding from secondary to primary and community services

The King’s Fund says a shift in focus away from hospital care in England’s ‘failing health and care system’ is essential.

My Top Five: Ophthalmology Twitter accounts

There are approximately 4.2 billion active social media users worldwide. This figure represents over half of the global population and is steadily rising [1]. There are currently over 217 million active Twitter users and given the platform’s versatility and ability...

My Top Five: Ophthalmology Twitter accounts

There are approximately 4.2 billion active social media users worldwide. This figure represents over half of the global population and is steadily rising [1]. There are currently over 217 million active Twitter users and given the platform’s versatility and ability...

Cyanoacrylate nail glue accidentally instilled into the eye instead of eye drops

Three hundred thousand cataract operations take place each year in the UK alone and each patient will receive a four week course of drops in order to cover them for any postoperative inflammation or infection. Accidental instillation of cyanoacrylate glue...

Inherited retinal disorders now the leading cause of blindness

The recent paper in BMJ Open, from the UCL Institute of Ophthalmology, ‘A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010’ concludes that inherited retinal disorders (IRD) such...