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Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Risks to visual function from blepharokeratoconjunctivitis

This study evaluated the prevalence of blepharokeratoconjunctivitis (BKC) and prevalence of amblyopic risk factors with comparison of these rates to rates in the general US paediatric population. The authors evaluated the rate of patient reported symptoms in patients with and...

Typical and atypical optic neuritis – diagnosis and initial management

Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

The results of the last survey Aug 2019

Thank you once again for participating in the survey. Some fascinating results once again. Almost one in five of us do not cancel cataract surgery on the day if the blood pressure (BP) is high, which I am surprised about....

White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...

Can 3D facial imaging improve patient management in disfiguring eye disease?

Fight for Sight is the leading UK charity funder of eye research. Since the 2013 Sight Loss and Vision Priority Setting Partnership we have encouraged our researchers to work on priorities jointly identified by people affected by sight loss and...

Two cases of acute syphilitic posterior placoid chorioretinitis

Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...

St John of Jerusalem Eye Hospital receives recognition and support

In 2017 the St John Ophthalmic Association (SOA) was established by ophthalmic practitioners across the world to support the St John of Jerusalem Eye Hospital Group. The purpose of the Association is to broaden the ophthalmic expertise available to St John and its staff.

Ocular surface special: Ocular manifestations of Stevens-Johnson syndrome

Stevens–Johnson syndrome (SJS) is an uncommon dermatological emergency on the same clinical spectrum as toxic epidermal necrolysis (TEN). SJS is characterised by an acute, immune-mediated attack on the skin and mucous membranes, producing a rapidly progressive erythematous eruption with blistering...

Developments in oculoplastic surgery

A study of NHS practice demonstrated significant patient-reported quality-of-life improvements from commonly performed oculoplastic operations: entropion repair, ectropion repair, ptosis repair and dacrocystorhinostomy (DCR) [1]. In recent years, surgical and non-surgical approaches to functional and aesthetic oculoplastic surgery have advanced...

Recurrent unilateral preseptal cellulitis secondary to herpes simplex virus infection

Introduction Periorbital (sometimes called preseptal cellulitis) is a common condition which on its own is not normally an ophthalmic or surgical emergency, however it has the potential to cause severe and serious morbidity in cases where the infection has crossed...