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Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy
In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...Eye News to partner with AOP Young Ophthalmologists Program
We are delighted to announce our partnership with the AOP (Advanced Ophthalmologic Practice) Academy Young Ophthalmologists event 'Retina: How to avoid false friends'.The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...
Importing iron to the retina
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
Detection of antiranibizumab antibodies in exudative AMD
In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...The College of Optometrists: Optometry Tomorrow 2024 (incorporating BCLA Focus)
by Claire McLoughlin, PR Manager, College of Optometrists, UK. The College of Optometrists and British Contact Lens Association (BCLA) welcomed around 900 attendees at Optometry Tomorrow 24 – now incorporating BCLA Focus – on 28–29 April. This was the 20th...
Ptosis frontalis sling surgery
In this retrospective study the authors investigated the functional and cosmetic outcomes of the modified frontalis sling procedure using silicone rods. The study included 17 patients (26 lids) and nine had bilateral surgery. An excellent outcome was defined as alignment...
IOOA and DVD surgery
The authors report the results of bilateral modified inferior oblique (IO) transposition considering the equator in seven patients with infantile strabismus syndrome with inferior oblique overaction (IOOA) and dissociated vertical deviation (DVD). Mean age was 4.5 years (2-7) and mean...
Short-term outcome after intravitreal ranibizumab injections for ROP
This is an interventional case series study of three premature babies (six eyes) with high risk prethreshold or threshold retinopathy of prematurity (ROP) with plus disease that received intravitreal ranibizumab injections for ROP. All infants received intravitreal ranibizumab injections of...
TED vertical strabismus surgery
This study reports the surgical experience with superior or inferior rectus resection to correct vertical strabismus associated with thyroid eye disease (TED). The study included eight female euthyroid patients (nine muscles) with mean age at surgery of 65±8.9 years and...
