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RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Conservative surgical management of optic disc pit maculopathy
Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...Four weeks to go until Optometry Tomorrow 2026
With just four weeks to go, now is the time to secure your place at Optometry Tomorrow 2026. The College of Optometrists' flagship conference takes place on 14 and 15 June at the Harrogate Convention Centre. Two days of learning,...A comparison of light sources in retinal imaging
Before starting to talk about the light sources present in retinal imaging, it is necessary to start from the base: the light. Light is an electromagnetic wave whose smallest part is the photon (or quantum of light). A high frequency...Chemical injury
You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....Time is vision in central retinal artery occlusion
Central retinal artery occlusion (CRAO) is a rare but devastating vascular episode that can have severe impact on vision. Treatment is very time-limited and needs to be initiated very quickly to salvage any vision. The majority of patients present to...Principles of contact lens fitting in keratoconus
Keratoconus is an ectatic condition of the cornea characterised by progressive conical distortion with irregular astigmatism, myopia and apical protrusion. Most cases progress slowly resulting in varying degrees of myopic astigmatism. Management of keratoconus includes spectacles, soft contact lenses, a...
