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MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...Cornea teaching techniques: one cornea donor tissue for two purposes
There is a national shortage in the UK in corneal graft material [1,2]. The majority (69%) of corneal transplants in the UK are partial thickness, with 35% being Descemet membrane endothelial keratoplasty (DMEK) [2]. During the preparation of the donor...First medical AI model with globally representative data
Quest to build the first medical AI foundation model with globally representative data. A research consortium of over 100 study groups in more than 65 countries has launched the Global RETFound initiative, a collaborative effort to develop the first globally...Preparing for the Duke Elder Award
The Duke Elder examination is an undergraduate ophthalmology exam, conducted by the Royal College of Ophthalmologists (RCOphth) and undertaken by students with an interest in ophthalmology. It is a two-hour, 90-question, multiple choice exam with a broader curriculum than that...Certifying patients as visually impaired: the start of a journey
In March 2017 there were 290,475 people registered as either visually impaired or severely visually impaired in the UK [1]. Patients registered as sight impaired benefit from financial support as well as practical help. Practical help is provided by social...21st Century retinal laser treatment in the anti-VEGF era
In today’s world, macular laser treatment has a vital role in the treatment of diabetic macular oedema (DMO). DMO is one of the most common causes of visual impairment. Despite expensive intravitreal treatment courses of anti-VEGF, many will agree that...Ambient scribes: The silent revolution
Clinical practice is in the midst of a profound digital transformation with a new wave of technology gaining increasing prominence: ambient scribes. These AI-powered tools streamline documentation by converting doctor–patient conversations into structured clinical notes in near real time. Healthcare...
