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Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Trabeculectomy with MMC in post-traumatic angle recession glaucoma

This study aimed to evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgery. Thirty-two phakic eyes of 32 patients who underwent trab MMC between January-2002 and...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Pilot trial of Fluoxetine for post-stroke homonymous hemianopia

The authors present a pilot randomised placebo controlled double blind trial assessing 20mg fluoxetine once daily for 90 days versus placebo in stroke survivors with isolated homonymous hemianopia. Exclusion criteria were extensive in terms of pre-existing ophthalmic or neurologic disease,...

Is intracranial pressure affected by the valsalva manoeuvres and exercise?

Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure (ICP), which leads to optic nerve head swelling and a risk of visual loss. The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to...

Comparison of motor and sensory outcomes for nonaccommodative esotropia and partial accommodative esotropia

Motor and sensory outcomes of surgery are compared for partial accommodative refractive esotropia (pARET) and acute nonaccommodative comitant esotropia (ANAET) to evaluate factors affecting their surgical success. This was a retrospective study of 38 ANAET (26 males, 12 females) and...

Correlations of fusional convergence with suppression depth in control of exotropia

This study was undertaken to investigate the differences in fusional convergence during refusion in patients with intermittent exotropia based on suppression depth and exotropia control. This was a cross-sectional study of 25 patients; 15 female and 10 male aged mean...

Samsung focuses on the sight impaired and internet security flaws

Smartphone assistive technology for the sight impaired In previous issues we’ve covered some specific smartphones that have been developed for the sight impaired. Samsung are now doing something similar, but in the form of accessories. In March 2014 they announced,...