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Prostaglandin-associated periorbitopathy

This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Development of testing protocols for high and low contrast visual acuity

Dysfunction of the afferent visual system, characterised by impairments in high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA) have been demonstrated in some neurological conditions such as multiple sclerosis and Parkinson’s disease. HCVA and LCVA are also potential quantitative...

ARN in North Africa

Acute retinal necrosis (ARN) is a rare cause of uveitis. This paper aims to outline the clinical features of 12 patients with ARN in a referral centre in Tunisia, North Africa. A retrospective review of case notes was carried out....

OCT positioning regimen in macular hole surgery

The authors set out to evaluate an OCT-based positioning regimen for macular hole surgery. Patients were advised to maintain prone positioning until the hole was confirmed to be closed based on daily OCTs. Surgery consisted of 23-gauge phacovitrectomy with internal...

OCTA use in CNV associated with CSR

The aim of this study was to assess the rate of choroidal neovascularisation (CNV) in chronic central serous chorioretinopathy (CSR) patients with flat irregular pigment epithelial detachments (PEDs) by optical coherence tomography angiography (OCTA). Data of all consecutive patients with...

Low dose steroids for ocular dry eye disease in graft vs. host disease

This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...

Sutureless 27-gauge needle intrascleral intraocular lens implantation

The authors report on a prospective, non-comparative, interventional case series of patients undergoing sutureless intrascleral fixation of a posterior chamber three piece intraocular lens (IOL) using a 27-gauge needle for docking. Sutureless techniques have the advantage of not having complex...

Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification

This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...

OCT measurements of eye muscles for Grave’s disease

The purpose of this study was to use optical coherence tomography (OCT) to assess horizontal rectus muscle thickening in patients with active and inactive Grave’s ophthalmopathy (GO) compared to healthy controls. This was a cross section observation study of rights...

Uveitis‐Glaucoma‐Hyphaemia syndrome retrospective case-control study

The authors present the findings of a case-control study aiming to assess uveitis‐glaucoma‐hyphaemia (UGH) syndrome, focusing on the resolution, glaucoma development and risk factors. The authors compared three groups each containing 71 patients. Each group contained patients with UGH syndrome,...

Correlation between aqueous flare and macular microvascular status in diabetes mellitus

The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...