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Tocilizumab in Graves’ orbitopathy
This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...
Natural history of optic nerve head drusen in a paediatric population
A retrospective case notes review is presented focusing on children diagnosed with optic nerve head drusen over an eight-year period. Inclusion criteria included cases coded for optic nerve head drusen and / or pseudopapilledema. The aim of the study was...
Medium-term outcomes following photo screening
A photo-screening project of preverbal children was conducted in 2016 in Portugal consisting of enrolment of two-year-old children and referral of these if having a positive screen to paediatric ophthalmology plus a screen of four-year-old children who missed or had...
Attracting workforce to paediatric ophthalmology
This was a survey-based study to address unanswered questions relating to economic and workforce issues in paediatric ophthalmology. The survey comprised 12 questions with yes / no or multiple-choice responses and was circulated to American Association for Pediatric Ophthalmology and...
Retinal nerve fibre layer thickness in migraine
The aim of this study is to evaluate retinal nerve fibre layer (RNFL) thickness changes in children with migraine compared to healthy controls and analyse RNFL changes dependent on type of migraine. This was an observation case control study of...
Outcomes for acute acquired non-accommodative comitant esotropia
Outcomes are reported in a retrospective review of 338 patients with acute acquired non-accommodative comitant esotropia (AACE). Mean age at presentation was 12.60 ±9.37 years and 220 were male, 118 female. Best corrected visual acuity was 0.2 ±0.29 logMAR overall;...
Refractive surgery for anisometropic amblyopia
The authors report the outcomes of refractive surgery with phakic intraocular lens (PIOL) implant for management of anisometropic amblyopia in children intolerant to conventional therapy. This was a retrospective study of 71 eyes of 71 patients of which 58 were...
Extraocular muscle disinsertion outcomes for large angle strabismus
The authors present a case series of patients who underwent surgical extraocular muscle (EOM) disinsertion for severe cranial nerve palsy or thyroid eye disease including 12 patients (13 eyes: 10 male, three female). There was one bilateral case – bilateral...
Features of branchio-oculo-facial syndrome
Branchio-oculo-facial (BOF) syndrome is an autosomal dominant inherited syndrome that typically presents with branchial cleft sinus defects, ocular anomalies and dysmorphic facial appearance. The authors present a new case alongside the results of a literature review describing the common genetic...
A review of neuro and retinal imaging findings in Alzheimer’s disease
The authors present a systematic review with the aim of assessing the relationship between retinal and cerebral changes in Alzheimer’s disease (AD), mild cognitive impairment and pre-clinical AD. A total of 23 articles met the inclusion criteria of the review,...
