You searched for "regenerative"

1417 results found

RPE tears after intravitreal Lucentis

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...

Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration

This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...

Glaucoma medications and ocular surface disease

This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...

Incidence and risk factors of ocular hypertension following PPV and SOI

In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...

A revolution in modern genetic testing for the clinical management of ocular disease

Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...

In conversation with Captain Gary Dyson

Captain Gary Dyson, Chief Pilot of the Orbis Flying Eye Hospital, spoke to Chris Henson about his 22-year stint flying the plane, its role at the cutting edge of aviation and medical technology, and how Orbis plan to continue to...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

NICE drugs: an update on what’s good to go

Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...

Guideline considerations for management of paediatric traumatic cataract

This study aimed to develop guidelines for preoperative decision-making and perioperative management of paediatric traumatic cataract patients. A 24-question survey was designed to assess surgeon background, preoperative planning and testing, surgical timing, intraoperative techniques and postoperative management. Anonymous responses were...

Intranasal combined dexmedetomidine and intranasal midazolam-ketamine sedation efficacy and associations in childhood strabismus surgery

The aim of this study was to compare the efficacy of intranasal combined dexmedetomidine (D) and intranasal midazolam-ketamine (MK) sedation and their effects on the occurrence of oculocardiac reflex in children’s strabismus surgery. The study recruited 37 children to each...