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Anti-VEGF agents treatment outcomes in macular telangiectasia

This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...

Type 3 macular neovascularisation (MNV) due to age-related macular degeneration

This paper systematically reviews and summarises the current knowledge on type 3 neovascularisation due to age-related macular degeneration which is defined as neovascularisation originating from the retinal deep capillary plexus that grows towards the outer retina often penetrating the level...

Sliding lower lid tarsal flap

This is a retrospective review of a lower lid reconstructive technique utilising a sliding tarsal flap. Thirty-two patients who had undergone Mohs surgery were included and each had a shallow marginal defect with at least one remaining tarsal edge having...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...

Ultrasound biomicroscopy (part 2): primary angle closure

Patients with primary angle closure or primary angle closure glaucoma [PAC(G)] comprise a significant subgroup affecting around 10% of glaucoma patients amongst Caucasians. Assessment of the patient with angle closure, or narrow angles, requires gonioscopy. However, whilst identifying the presence...

Imaging papilloedema vs. pseudo-papilloedema

Quite often, in the working week as an ophthalmic photographer, you will be given that patient with ‘swollen discs’ to image. These swollen discs could be a number of things, but mainly fall into one of two categories: papilloedema or...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Radiation retinopathy

The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...

Finasteride and central serous chorioretinopathy

The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...

Needling procedure for failed bleb

The aim of this study was to determine the efficacy of needling with 5-FU after failed filtering procedures in the paediatric population. This was a retrospective review of 324 filtration surgeries in 265 children with 55 eyes (16.9%) undergoing needling...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...