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Familial Mediterranean Fever and keratoconus

This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

Corpus callosum in infantile esotropia

Diffusion tensor imaging (DTI) imaging was undertaken with four infantile esotropia (IE) patients and nine controls. All with IE showed an asymmetrical distribution of callosal fibres when comparing two hemispheres. Many fibres terminated near the tips of the occipital cortices....

Diagnosis and management of paediatric keratoconus

This article reviews the current literature on paediatric keratoconus diagnosis and management. Paediatric cases pose challenges as they may not vocalise unilateral changes, difficulty in obtaining reliable imaging, faster rates of progression, difficultly with contact lenses and presumed worse outcomes...

International medical graduates in ophthalmology

IMGs in the NHS The General Medical Council (GMC) defines an international medical graduate (IMG) as someone who has obtained their primary medical qualification outside the European Economic Area (EEA) [1], meaning that an IMG is a medical doctor whose...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Paediatric optic disc anomalies

Anomalies of the optic nerve are relatively rare, but account for a significant proportion of sight impairment in children and adults. The recognition of these anomalies by eye health professionals is important not only due to their potential impact on...

Medical Ophthalmological Society (MOSUK) Meeting: 22 March 2023

This year’s meeting takes place on 22 March 2023, and showcases the interdisciplinary breadth of medical ophthalmology.

SightCare Awards shortlist announced

SightCare, the UK’s leading provider of business and networking services to independent optometrists and opticians, is excited to announce the shortlisted entries to our prestigious awards, celebrating excellence in the independent optical sector. Now in their fifth successful year, the...

In conversation with Dr Robert B Nussenblatt

Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...

How good does my vision have to be to drive this thing? Visual standards for various occupations

We can all picture that moment in clinic: you are about to tell someone that they’re no longer legally able to drive, ready to deploy our ‘breaking bad news’ techniques. For some patients this may have been expected, or they...

The reps

Who are the reps? Every one of us knows the friendly face of the local randomprost eye drop representative or the nice man from that eye lubricant company. These company representatives travel up and down the region with a smile,...