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Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

Ocular findings in children with myasthenia

This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...

Macular measurements for amblyopic eyes

This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...

Disc-fovea angle measurements for objective cyclotorsion review

The author measured the disc-fovea angle (DFA) in 249 healthy people (81 male, 168 female) as part of a retrospective study of 44 to 70-year-old adults. These were grouped as (1) aged 44 / 45 years, (2) aged 59-70 years,...

Ocular motility parameters in phakic and pseudophakic older people

The aim of this study was to compare the extent of phoria, strabismus and convergence of pseudophakic vs phakic people in an elderly population. The study was part of the Tehran Geriatric Eye Study (TGES). Of 3791 invitees, 3310 participated...

Case reports of neuro-visual consequences of mild COVID-19 in children

Neuro-visual involvement has been reported in numerous patients with severe SARS-CoV-2 disease, mainly among adult patients. In children, such involvement has been reported in rare cases, often in those presenting with severe forms of COVID-19. The aim of this work...

Using a tumour registry to investigate optic nerve gliomas

This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...

Tutopatch® in surgical management of third nerve palsy

his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...

Bromfenac versus betamethasone in diabetic macular oedema

This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...

Should we be looking for anemia in the presence of papilloedema?

The authors present a retrospective case notes review of patients diagnosed with idiopathic intracranial hypertension (IIH) presenting to a tertiary neuro-ophthalmology clinic over a 32-month period. The IIH group were age and sex matched with other patients attending the clinic...

Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...