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The 2020 Milgram Experiment
Will ophthalmology recover from COVID-19? Learning Curve columnist Gwyn Samuel Williams shares his thoughts on the developing impact of the pandemic “It’s busy today,” the nurse in green chuckles. “There are six patients I think.” Six. This clinic is designed...Obituary: Sohan Singh Hayreh (1927 - 2022)
Sohan would have been 95 on 6 November this year, but due to complications of COVID-19, he passed away on 29 September.BMLA Annual Conference & Educational Courses
Navroz Singh, core surgical trainee at Kings College NHS Trust. This year’s British Medical Laser Association (BMLA) annual conference was held over three days in a beautiful venue overlooking a sunny Cardiff Bay. It was attended by individuals hailing from...Breakthroughs in the genetics of angle-closure glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...What's trending Feb/Mar 2022
A round-up of the eye-related hot topics that have been trending over the last few weeks. British man fitted with 3D printed eye Steve Verze of London has required a prosthetic eye for over 20 years. On 25 November 2021,...The world in union
"It’s the world in union, the world as one…” Hearing these lyrics as a sports fan means only one thing: it’s time for the Rugby World Cup! This four-yearly sporting extravaganza should hit your TV screens around the same time...Dolby’s Sound of a Masterpiece: Hear what Da Vinci's Mona Lisa and Monet's Water-Lily Pond sound like
Dolby Laboratories and Royal National Institute of Blind People (RNIB) have reimagined the world’s most famous artwork masterpieces - from Da Vinci’s Mona Lisa to David Hockney’s A Bigger Splash - to create an immersive soundtrack, in state-of-the-art Dolby Atmos...
Online retinoblastoma surveillance tool
Given the vision and life-threatening course of retinoblastoma (RB), it has become a significant heritable childhood cancer to screen for. To recommend surveillance, risk must be estimated and genetic testing plays a vital role. However, genetic tests vary based on...
OCTA in angioid streaks
This paper reports on the optical coherence tomography angiography (OCTA) features of choroidal neovascularisation (CNV) secondary to angioid streaks and the ability to predict CNV activity. A total of 38 eyes of 19 patients were included in the study. Thirty...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
