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Macular pigment in relatives of AMD patients

Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...

Driving with retinitis pigmentosa

The authors present a study of 228 consecutive patients with a clinical or genetic diagnosis of retinitis pigmentosa. Data was collected prospectively between January 2012 and October 2022 in Perth, Australia. The study aimed to determine the proportion of patients...

The Gambia-Swansea VISION 2020 LINK: building eye care services and international friendships

History The VISION 2020 LINK between the Sheikh Zayed Regional Eye Care Centre (SZRECC), Banjul, The Gambia and the Ophthalmology Department, Singleton Hospital, Swansea started in 2008 under the guidance of the VISION 2020 LINKS Programme at the International Centre...

Low Vision Questionnaire

Participation in this survey is greatly appreciated and will help eyecare practitioners to provide the support patients with vision loss deserve.

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Biopsy of nasolacrimal duct using sheath guided dacryoendoscopy

In this study the author’s biopsied six eyes of five individuals with recurrent nasolacrimal duct obstruction following a prior dacryoendoscopic probing. All procedures were performed under local anaesthetic, the obstruction or lesion was directly visualised with dacryoendoscope and biopsy was...

Comparison of false-negative responses in glaucoma patients and normal observers

The authors compared false negative rates for full threshold (FULL) and Swedish Interactive Threshold Algorithm (SITA) standard automated perimetry in healthy control subjects and glaucoma patients. Twenty-four subjects underwent visual field testing of one eye five times within six weeks...

Scheimpflug images and graft rejection

This study aimed to assess corneal changes using 360-degree Scheimpflug images and pachymetry readings to outline screening parameters, which define graft rejection. Seventeen eyes of 16 patients developed clinically manifest allograft rejection two to 42 months after surgery – those...

The inflammatory side-effect of Brimonidine

Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...

How are pigment dispersion syndrome and pigmentary glaucoma inherited?

This single centre prospective, cross-sectional study assessed the relatives of patients with pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) to determine the heritability of these conditions over an 11 month period. One hundred and one unrelated patients with PDS...

Saccadic duration and trajectories in monkeys with induced strabismus

This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large...

Histopathological changes in rabbit retinitis pigmentosa

The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...