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Effects of blood donation on the physiology of the eye
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...Myasthenia Gravis Masquerading as a Third Cranial Nerve Palsy
A 65-year-old man presented with a week’s history of binocular diplopia (in all directions of gaze) and a right partial ptosis. He was systemically well. His past medical history was unremarkable except for vitiligo. At presentation acuity was 6/6 bilaterally....
Intravitreal dexamethasone implant for diabetic macular oedema
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...
One-year result of XEN45 implant for glaucoma: efficacy, safety, and postoperative management
The authors report a retrospective, non-randomised interventional case series of 39 patients who underwent a standalone XEN45 implantation. All 39 patients (female: male=1.2: 1) completed 12-month follow-up. Mean age was 70.1 years (range 32–92). Primary outcome measures were the intraocular...The International Council of Ophthalmology: what is it and is it useful for UK ophthalmologists?
ICO Director for Examinations and Assessments, Simon Keightley, explains the history and role of the organisation today, as well as outlining recent changes to the ICO examinations. The International Council of Ophthalmology (ICO) is the only international medical specialty organisation...
OCTA and pigment epithelium detachments
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
Medial rectus inferior half plication surgery for near exotropia
In this study the authors report a relatively new surgical treatment for near exotropia. The study included 17 patients: four with previous surgery and all with medial rectus injection of bupivacaine to reduce the angle of deviation. Treatment involved inferior...
Inferior oblique adherence syndrome
A case is reported of a 14-year-old with inferior oblique muscle adherence and fat adherence following unilateral inferior oblique (IO) anteriorisation. Following surgery, the patient developed consecutive esotropia, ptosis and marked limitation of laevoelevation. Forced duction test was positive for...Ocular manifestations of multiple sclerosis: an overview
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...
Brown’s syndrome surgery
Complications of surgery for Brown syndrome include under correction, extrusion of expanders and training for surgery. The authors introduced a procedure with minimal side-effects, accompanied by the application of the native tendon for superior oblique elongation. This was a prospective...
Saccadic duration and trajectories in monkeys with induced strabismus
This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large...
